diff --git a/base/compiler/abstractinterpretation.jl b/base/compiler/abstractinterpretation.jl
index 0e57f01bfbd12..99f3742a8f13f 100644
--- a/base/compiler/abstractinterpretation.jl
+++ b/base/compiler/abstractinterpretation.jl
@@ -1153,8 +1153,11 @@ function semi_concrete_eval_call(interp::AbstractInterpreter,
                 # that are newly resovled by irinterp
                 # state = InliningState(interp)
                 # ir = ssa_inlining_pass!(irsv.ir, state, propagate_inbounds(irsv))
-                new_effects = Effects(result.effects; nothrow)
-                return ConstCallResults(rt, SemiConcreteResult(mi, ir, new_effects), new_effects, mi)
+                effects = result.effects
+                if !is_nothrow(effects)
+                    effects = Effects(effects; nothrow)
+                end
+                return ConstCallResults(rt, SemiConcreteResult(mi, ir, effects), effects, mi)
             end
         end
     end
diff --git a/test/compiler/effects.jl b/test/compiler/effects.jl
index 2cf421073a166..44554690b1b98 100644
--- a/test/compiler/effects.jl
+++ b/test/compiler/effects.jl
@@ -1010,3 +1010,16 @@ end |> !Core.Compiler.is_nothrow
 @test Base.infer_effects() do
     getglobal(@__MODULE__, :my_defined_var, :foo, nothing)
 end |> !Core.Compiler.is_nothrow
+
+# irinterp should refine `:nothrow` information only if profitable
+Base.@assume_effects :nothrow function irinterp_nothrow_override(x, y)
+    z = sin(y)
+    if x
+        return "julia"
+    end
+    return z
+end
+@test Base.infer_effects((Float64,)) do y
+    isinf(y) && return zero(y)
+    irinterp_nothrow_override(true, y)
+end |> Core.Compiler.is_nothrow