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I'm designing antibody for my protein using RFdiffusion and ProteinMPNN.
subsequently, I'm predicting the structure of the sequence obtained from proteinMPNN using colabfold alphafold multimer.
I have a question about the structure obtained from colabfold alphafold multimer.
first, my protein is dimer. so, I predict that, designed antibody interacts only one protomer of dimer.
however, designed antibody seems to combine (interact) center of the dimer.
I think the antibody is slightly shifted.
Is there any solution?
What can I try?
The text was updated successfully, but these errors were encountered:
Hi,
I'm designing antibody for my protein using RFdiffusion and ProteinMPNN.
subsequently, I'm predicting the structure of the sequence obtained from proteinMPNN using colabfold alphafold multimer.
I have a question about the structure obtained from colabfold alphafold multimer.
first, my protein is dimer. so, I predict that, designed antibody interacts only one protomer of dimer.
however, designed antibody seems to combine (interact) center of the dimer.
I think the antibody is slightly shifted.
Is there any solution?
What can I try?
The text was updated successfully, but these errors were encountered: